Endocrine Abstracts

Aim: To evaluate the efficacy and safety for first patients treated in our clinic with liraglutide.Methods: Retrospective study of patients who started treatment with liraglutide in the last year in our department. We collected data on age, years of evolution, chronic complications, previous treatment, physical examination, analytical parameters and side effects.Results: Fifty-four patients. Follow-up: 4–12 months. Mean age: 5...

Background: The incidence of thyroid cancer (TC) has been increasing in recent years while mortality has remained stable. The cause of this increase is unclear, although several hypotheses have been proposed. While the increased incidence may only be apparent due to increased testing, there is data that suggest that there may be a real increase in incidence related to different risk factors. The aim of this meta-analysis was to determine the current incidence of TC in Europe.<...

The use of Flash Glucose Monitoring system (FGM) for the management of type 1 diabetes mellitus (T1D) is rapidly increasing. FGM enables people with diabetes to regularly track their glucose levels without needing to perform capillary finger-stick measurements (SMBG). Clinical studies have shown improvement of glycemic control and hypoglycemia reduction, as well as better comfort and quality of life in people with type 1 diabetes (T1D) using this technology. Objectives: to ass...

Objectives: The gestations in patients with type 1 diabetes are associated with an increase in maternal-fetal complications. Adequate glycemic control during pregnancy has been shown to reduce adverse events. Given that, the treatment with insulin pump improves glycemic control and that pregnancy implies constant changes in insulin resistance, our objective is to analyze the changes in insulin requirements in pregnant patients under CSII.Materials and me...

Introduction: Immune checkpoint inhibitors (ICIs) are an effective treatment for advanced cancer, but they are not free from immune-related adverse events (irAEs). A common irAES is thyroid dysfunction (TD-irAEs) and, as such, may influence patient survival and response to ICIs.Objetives: The aim was to determine the incidence and characteristics of TD-irAEs among patients with advanced cancer treated with ICIs in a real-life setting and to investigate t...

Introduction: Women with gestational diabetes mellitus (GDM) have an increased risk for developing glucose intolerance in postpartum. The aim of our study was to describe the general characteristics of pregnant women with GDM and to assess the prevalence of glucose intolerance in early postpartum by postpartum oral glucose tolerance test (ppOGTT).Methods: Retrospective study from January 2017 to December 2020 including patients with GDM followed at endoc...

Introduction: An increased risk of thyroid disease (TD) has been described in patients with type 1 diabetes (DM1) with respect to the general population. The objective is to establish the incidence and characterize the differences in patients who develop TD in relation to the debut of DM1 (previous, concurrent or a posteriori).Materials and methods: Retrospective study of 1126 patients followed up in Endocrinology consultations in Navarra. Three types of...

Aim: Non-alcoholic fatty liver disease (NAFLD) and type 2 Diabetes (T2D) are common conditions that frequently co-exist. Studies have shown an increase likelihood of micro and macrovascular complications in this population, as well, as an increased risk of developing more severe forms of liver disease. The aim of this study was to identify diabetic complications in patients with both diseases and search for an association with liver stiffness assessed by Liver Elastography (LE...

Aim: A key diagnostic step to determine the cause of hyperthyroidism is the measurement of circulating thyroid-stimulating immunoglobulin (TSI). High levels are associated with Graves’ disease (GD). A thyroid scintigraphy (TRS) is recommended when TSI is absent or its measurement unavailable, as TRS is capable of differentiating between GD (diffuse uptake) and toxic goitre (TG) (patchy uptake). Nevertheless, and while rarely necessary, histopathology remain the best metho...

Objective: The aim of this study is to evaluate clinical characteristics of patients diagnosed of follicular thyroid carcinoma and to study factors that are associated with a worse prognosis of the disease.Methods: We included 153 patients diagnosed of follicular thyroid carcinoma in our centre between January 1985 and December 2016. The baseline characteristics of the patients, and their long-term outcomes were collected. The mean follow-up was 15.2 yea...